| Preferred Name |
professional antigen presenting cell |
| Synonyms |
APC |
| Definitions |
A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. |
| ID |
http://purl.obolibrary.org/obo/CL_0000145 |
| comment |
Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. |
| capable of | |
| definition |
A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. |
| has_broad_synonym |
APC |
| has_obo_namespace |
cell |
| label |
professional antigen presenting cell |
| prefixIRI |
CL:0000145 |
| prefLabel |
professional antigen presenting cell |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/CL_0000145 | Phenotypic Quality Ontology | LOOM | |
| http://purl.obolibrary.org/obo/CL_0000145 | Phenotypic Quality Ontology | SAME_URI | |
| http://purl.obolibrary.org/obo/CL_0000145 | Human Disease Ontology 123 | LOOM | |
| http://purl.obolibrary.org/obo/CL_0000145 | Human Disease Ontology 123 | SAME_URI |