Cell Ontology

Last uploaded: February 23, 2022
Preferred Name

granulocyte monocyte progenitor cell

Synonyms

granulocyte-macrophage progenitor

granulocyte/monocyte precursor

colony forming unit granulocyte macrophage

CFU-C , Colony forming unit in culture

CFU-GM

GMP

granulocyte/monocyte progenitor

Definitions

Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1.

ID

http://purl.obolibrary.org/obo/CL_0000557

comment

Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.

capable of

http://purl.obolibrary.org/obo/GO_0030851

http://purl.obolibrary.org/obo/GO_0030225

definition

A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1.

has part

http://purl.obolibrary.org/obo/PR_000001944

http://purl.obolibrary.org/obo/PR_000005307

has plasma membrane part

http://purl.obolibrary.org/obo/PR_000001865

has_broad_synonym

CFU-C , Colony forming unit in culture

has_exact_synonym

granulocyte-macrophage progenitor

granulocyte/monocyte precursor

colony forming unit granulocyte macrophage

CFU-GM

GMP

granulocyte/monocyte progenitor

has_obo_namespace

cell

label

granulocyte monocyte progenitor cell

lacks_part

http://purl.obolibrary.org/obo/PR_000007857

http://purl.obolibrary.org/obo/PR_000007858

prefixIRI

CL:0000557

prefLabel

granulocyte monocyte progenitor cell

subClassOf

http://purl.obolibrary.org/obo/CL_0000763

http://purl.obolibrary.org/obo/CL_0011026

http://purl.obolibrary.org/obo/CL_0002032

http://purl.obolibrary.org/obo/CL_0001012

http://purl.obolibrary.org/obo/CARO_0000006

http://purl.obolibrary.org/obo/CL_1001610

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http://purl.obolibrary.org/obo/CL_0000557 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/CL_0000557 Phenotypic Quality Ontology SAME_URI