loading...| Preferred Name |
integrin alpha-M |
| Synonyms |
CD11b CR3A CD11B cell surface glycoprotein MAC-1 subunit alpha neutrophil adherence receptor ITGAM CR-3 alpha chain CD11 antigen-like family member B leukocyte adhesion receptor MO1 |
| Definitions |
Category=gene. Requested by=CL. An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. |
| ID |
http://purl.obolibrary.org/obo/PR_000001012 |
| comment |
Category=gene. Requested by=CL. |
| database_cross_reference |
IUPHARobj:2452 |
| definition |
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. |
| has_exact_synonym |
CD11b cell surface glycoprotein MAC-1 subunit alpha neutrophil adherence receptor ITGAM CR-3 alpha chain CD11 antigen-like family member B leukocyte adhesion receptor MO1 |
| has_obo_namespace |
protein |
| has_related_synonym |
CR3A CD11B |
| id |
PR:000001012 |
| label |
integrin alpha-M |
| notation |
PR:000001012 |
| prefLabel |
integrin alpha-M |
| subClassOf |