loading...| Preferred Name |
CD3 subunit with immunoglobulin domain |
| Synonyms |
CD3 subunit with Ig-like domain |
| Definitions |
A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. Category=family. |
| ID |
http://purl.obolibrary.org/obo/PR_000001018 |
| comment |
Category=family. |
| database_cross_reference |
PIRSF:PIRSF001993 |
| definition |
A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. |
| has_exact_synonym |
CD3 subunit with Ig-like domain |
| has_obo_namespace |
protein |
| id |
PR:000001018 |
| label |
CD3 subunit with immunoglobulin domain |
| notation |
PR:000001018 |
| prefLabel |
CD3 subunit with immunoglobulin domain |
| subClassOf |