loading...| Preferred Name |
secondary cultured cell population |
| Definitions |
The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. |
| ID |
http://purl.obolibrary.org/obo/OBI_0001905 |
| comment |
The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. |
| definition source |
PERSON:Matthew Brush PERSON:Matthew Brush |
| editor preferred label |
secondary cultured cell population 二次培养细胞群 |
| has curation status | |
| has grain | |
| is_specified_output_of | |
| label |
secondary cultured cell population 二次培养细胞群 |
| prefixIRI |
OBI:0001905 |
| prefLabel |
secondary cultured cell population |
| textual definition |
A cultured cell population that is derived through one or more passages in culture. 通过一次或多次培养得到的一个培养细胞群。 |
| 引自 | |
| 替代术语 |
二次细胞培养样品 secondary cell culture sample |
| 术语编辑者 |
PERSON:Matthew Brush PERSON:Matthew Brush |
| 编者注 |
术语“次生细胞培养物” 通常用于生物学文本/协议中以指代初始传代后的任何细胞培养物。 我们把它包括在内，因为在初级培养和建立一个稳定的同质细胞系之间要经历很多代。 这样的培养物被认为是“次生培养物”； 但不是“细胞系”； 在它们的衍生物从“原代细胞培养物”到“细胞系”的中间传代/选择期间，这是更具体类型的次生培养物。 The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. |
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