loading...| Preferred Name |
cultured cell population |
| Definitions |
A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. |
| ID |
http://purl.obolibrary.org/obo/OBI_0100060 |
| comment |
The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally. “培养细胞群”的范围仅限于所有细胞成员必须共享一个增殖历史（即通过一个原始培养物的一个共同的谱系衍生）。在这样定义下，这个类可以用来指研究人员在科学实践中实际使用的群体—即培养、实验和共享的投入。这些群体中的细胞将是相对均匀的群体，因为它们经历连续的共同增殖而经历了类似的选择压力。这个群体也会有一个单一的数字，同样是由于他们共同的增殖史。培养细胞群仅代表细胞的集合（即，不包括培养基，培养皿等），并且包括培养的单细胞生物或培养的多细胞生物细胞的群体。它们可以在活跃的细胞培养中存在，以静止的状态存储以供将来使用，或者应用于实验。 |
| definition source |
PERSON:Matthew Brush |
| editor preferred label |
培养细胞群 cultured cell population |
| example of usage |
A cultured cell population applied in an experiment: "293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest." (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948). A cultured cell population maintained in vitro: "Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks" (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293). 在实验中应用的培养细胞群体：“表达TrkA的293细胞血清饥饿18小时，然后在细胞收获之前加入神经营养因子10分钟。” (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948). 体外维持的培养细胞群体：“来自15天胚胎的大鼠皮层神经元在解离的细胞培养物中生长并在体外维持8-12周” (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293). |
| has curation status | |
| has grain | |
| is_specified_output_of | |
| label |
培养细胞群 cultured cell population |
| prefixIRI |
OBI:0100060 |
| prefLabel |
cultured cell population |
| textual definition |
A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. 由一种培养细胞集合构成的加工材料，这些细胞在培养中一直保持在一起，并具有共同的增殖历史。 |
| 引自 | |
| 替代术语 |
细胞培养样品 cell culture sample |
| 术语编辑者 |
PERSON:Matthew Brush |
| 编者注 |
2013-6-5 MHB：这个OBI类以前被称为“细胞培养”，但标签在2013年春季CLO比对工作之后发生了变化和定义更新，在此期间本类的意图被澄清，指的是培养的某些部分或而不是一个完整的细胞培养或细胞系。 2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line. |
| subClassOf |