loading...| Preferred Name |
CD3 subunit with immunoglobulin domain |
| Synonyms |
具有Ig样结构域的CD3亚基 CD3 subunit with Ig-like domain |
| Definitions |
A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. |
| ID |
http://purl.obolibrary.org/obo/PR_000001018 |
| label |
具有免疫球蛋白域的CD3亚单位 CD3 subunit with immunoglobulin domain |
| prefixIRI |
PR:000001018 |
| prefLabel |
CD3 subunit with immunoglobulin domain |
| textual definition |
A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. 具有采用一个免疫球蛋白折叠的一个细胞外N端结构域，一个跨膜结构域和一个细胞内C端结构域组成的一个核心结构域的蛋白质，其中细胞内C末端结构域有基于免疫受体酪氨酸的激活基序（Pfam：PF02189）的一个拷贝。它构成T细胞抗原受体（TCR）的不变亚基。 TCR是T细胞上的表面受体，负责识别MHC限制性抗原并启动细胞免疫应答。 |
| 引自 | |
| 有_精确的_同义词 |
具有Ig样结构域的CD3亚基 CD3 subunit with Ig-like domain |
| subClassOf |