loading...| Preferred Name |
rhodopsin-like G-protein coupled receptor |
| Synonyms |
1类G蛋白偶联受体 fam:rhodopsin |
| Definitions |
Category=family. Classification based on GRAFS system. [PMID:12761335] |
| ID |
http://purl.obolibrary.org/obo/PR_000001094 |
| comment |
Category=family. Classification based on GRAFS system. [PMID:12761335] |
| database_cross_reference |
PIRSF:PIRSF800006 |
| id |
PR:000001094 |
| label |
rhodopsin-like G-protein coupled receptor 视紫红质样G蛋白偶联受体 |
| notation |
PR:000001094 |
| prefLabel |
rhodopsin-like G-protein coupled receptor |
| textual definition |
包含7个跨膜受体（视紫红质家族）结构域（Pfam：PF00001）的G蛋白偶联受体，其包含7个在螺旋之间具有3个胞内环（IL1-IL3）和3个胞外环（EL1-EL3）的跨膜螺旋（TMI-TM7）。氨基末端区域是细胞外的，羧基末端区域是细胞内的。视紫红质样G蛋白偶联受体（GPCR）在几类GPCR中是唯一的，其中大多数具有非常短的氨基末端区段和几个特征序列基序，特别是在TM7中的NSxxNPxxY和TM3与IL2环之间的D/E-R-Y/F 。大多数在TM区域间的一个空腔内与其配体结合。 A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions. |
| 引自 |
http://purl.obolibrary.org/obo/pr.owl |
| 有_obo_命名空间 |
protein |
| 有_精确的_同义词 |
1类G蛋白偶联受体 fam:rhodopsin class 1 G-protein coupled receptor FAM：视紫红质 |
| subClassOf |