Preferred Name

CSF-1/PDGF receptor-type tyrosine-protein kinase

Definitions

具有由信号序列,5个Ig样结构域,其后的一个跨膜序列,及一个蛋白酪氨酸激酶结构域(Pfam:PF07714)组成核心结构的蛋白质。然而,在大多数序列中,只有1-3个Ig结构域被Pfam HMM检测到。 Pfam:PF00047是最常见的,该Ig域的其他成员但也可识别,Pfam:PF07679和Pfam:PF07686可以识别出。第四个Ig结构域缺少二硫键结合的半胱氨酸。 A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines.

ID

http://purl.obolibrary.org/obo/PR_000001810

label

CSF-1/PDGF receptor-type tyrosine-protein kinase

CSF-1/PDGF受体酪氨酸蛋白激酶

prefixIRI

PR:000001810

prefLabel

CSF-1/PDGF receptor-type tyrosine-protein kinase

textual definition

具有由信号序列,5个Ig样结构域,其后的一个跨膜序列,及一个蛋白酪氨酸激酶结构域(Pfam:PF07714)组成核心结构的蛋白质。然而,在大多数序列中,只有1-3个Ig结构域被Pfam HMM检测到。 Pfam:PF00047是最常见的,该Ig域的其他成员但也可识别,Pfam:PF07679和Pfam:PF07686可以识别出。第四个Ig结构域缺少二硫键结合的半胱氨酸。

A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines.

引自

http://purl.obolibrary.org/obo/clo.owl

http://purl.obolibrary.org/obo/cl.owl

subClassOf

http://purl.obolibrary.org/obo/PR_000000001

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http://purl.obolibrary.org/obo/PR_000001810 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001810 International Classification of Diseases Ontology SAME_URI
http://purl.obolibrary.org/obo/PR_000001810 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001810 Phenotypic Quality Ontology SAME_URI
http://purl.obolibrary.org/obo/PR_000001810 Cell Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001810 Cell Ontology SAME_URI
http://purl.obolibrary.org/obo/PR_000001810 Protein Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001810 Protein Ontology SAME_URI
http://purl.obolibrary.org/obo/PR_000001810 Cell Line Ontology (Chinese Translation) SAME_URI