loading...| Preferred Name |
tetanus |
| Synonyms |
Infection due to Clostridium tetani |
| Definitions |
A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli. |
| ID |
http://purl.obolibrary.org/obo/DOID_11338 |
| database_cross_reference |
UMLS_CUI:C0039614 ICD10CM:A35 NCI:C85185 GARD:5144 MESH:D013742 SNOMEDCT_US_2022_09_01:154312006 ICD9CM:037 |
| definition |
A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli. |
| has exact synonym |
Infection due to Clostridium tetani clostridial tetanus |
| has material basis in | |
| has_obo_namespace |
disease_ontology |
| id |
DOID:11338 |
| in_subset |
http://purl.obolibrary.org/obo/doid#gram-positive_bacterial_infectious_disease http://purl.obolibrary.org/obo/doid#DO_rare_slim http://purl.obolibrary.org/obo/doid#NCIthesaurus http://purl.obolibrary.org/obo/doid#DO_infectious_disease_slim |
| label |
tetanus |
| notation |
DOID:11338 |
| prefLabel |
tetanus |
| subClassOf |