malignant hyperthermia

malignant hyperpyrexia due to anesthesia

Xref MGI. OMIM mapping confirmed by DO. [SN]. A muscle tissue disease that is characterized by a drastic and uncontrolled increase in skeletal muscle oxidative metabolism, which overwhelms the body's capacity to supply oxygen, remove carbon dioxide, and regulate body temperature and that has_material_basis_in heterozygous mutation in the ryanodine receptor gene (RYR1) on chromosome 19q13. Manifestations of malignant hyperthermia (MH) are precipitated by certain volatile anesthetics (i.e., halothane, isoflurane, sevoflurane, desflurane, enflurane), either alone or in conjunction with a depolarizing muscle relaxant (specifically, succinylcholine).

http://purl.obolibrary.org/obo/DOID_8545

Xref MGI. OMIM mapping confirmed by DO. [SN].

MESH:D008305

ORDO:423

SNOMEDCT_US_2022_09_01:111738008

UMLS_CUI:C0024591

ICD9CM:995.86

OMIM:PS145600

ICD10CM:T88.3

NCI:C84869

GARD:6964

A muscle tissue disease that is characterized by a drastic and uncontrolled increase in skeletal muscle oxidative metabolism, which overwhelms the body's capacity to supply oxygen, remove carbon dioxide, and regulate body temperature and that has_material_basis_in heterozygous mutation in the ryanodine receptor gene (RYR1) on chromosome 19q13. Manifestations of malignant hyperthermia (MH) are precipitated by certain volatile anesthetics (i.e., halothane, isoflurane, sevoflurane, desflurane, enflurane), either alone or in conjunction with a depolarizing muscle relaxant (specifically, succinylcholine).

malignant hyperpyrexia due to anesthesia

anesthesia related hyperthermia

http://purl.obolibrary.org/obo/GENO_0000147

disease_ontology

DOID:8545

http://purl.obolibrary.org/obo/doid#DO_rare_slim

http://purl.obolibrary.org/obo/doid#NCIthesaurus

malignant hyperthermia

DOID:8545

malignant hyperthermia

http://purl.obolibrary.org/obo/DOID_66

http://purl.obolibrary.org/obo/DOID_0050736