Human Phenotype Ontology

Last uploaded: February 24, 2022
Preferred Name

Choanal atresia

Synonyms

Blockage of the rear opening of the nasal cavity

Definitions

Absence or abnormal closure of the choana (the posterior nasal aperture). Most embryologists believe that posterior choanal atresia results from a failure of rupture between the 35th and 38th day of fetal life of the partition which separates the bucconasal or buccopharyngeal membranes. The resultant choanal atresia may be unilateral or bilateral, bony or membranous, complete or incomplete. In over 90 per cent of cases the obstruction is bony, while in the remainder it is membranous. The bony type of atresia is commonly located 1-2 mm. anterior to the posterior edge of the hard palate, and the osseous septum varies in thickness from 1 to 10 mm. In the membranous form of choanal atresia the obstruction usually occurs further posteriorly. In approximately one third of cases the atresia is bilateral.

ID

http://purl.obolibrary.org/obo/HP_0000453

database_cross_reference

MSH:D002754

Fyler:4203

UMLS:C0008297

SNOMEDCT_US:204508009

definition

Absence or abnormal closure of the choana (the posterior nasal aperture). Most embryologists believe that posterior choanal atresia results from a failure of rupture between the 35th and 38th day of fetal life of the partition which separates the bucconasal or buccopharyngeal membranes. The resultant choanal atresia may be unilateral or bilateral, bony or membranous, complete or incomplete. In over 90 per cent of cases the obstruction is bony, while in the remainder it is membranous. The bony type of atresia is commonly located 1-2 mm. anterior to the posterior edge of the hard palate, and the osseous septum varies in thickness from 1 to 10 mm. In the membranous form of choanal atresia the obstruction usually occurs further posteriorly. In approximately one third of cases the atresia is bilateral.

has_alternative_id

HP:0004496

HP:0000416

HP:0004503

has_exact_synonym

Blockage of the rear opening of the nasal cavity

has_obo_namespace

human_phenotype

id

HP:0000453

in_subset

http://purl.obolibrary.org/obo/hp.obo#hposlim_core

label

Choanal atresia

notation

HP:0000453

prefLabel

Choanal atresia

treeView

http://purl.obolibrary.org/obo/HP_0000415

subClassOf

http://purl.obolibrary.org/obo/HP_0000415

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/MESH/D002754 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU036653 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/DOID_9574 Human Disease Ontology 123 LOOM
http://purl.bioontology.org/ontology/ICD10CM/Q30.0 International Classification of Diseases, Version 10 - Clinical Modification LOOM
http://purl.bioontology.org/ontology/ICD10/Q30.0 International Classification of Diseases, Version 10 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/LA70.2 International Classification of Diseases, 11th Edition, China LOOM