Abnormal glomerular mesangium morphology

Abnormality of the glomerular mesangium

Mesangial abnormality

Abnormality glomerular mesangium morphology

An abnormality of the mesangium, i.e., of the central part of the renal glomerulus between capillaries. Mesangial cells constitute the central stalk of the glomerulus and are in continuity with the extraglomerular mesangium and the juxtaglomerular apparatus. They have contractile properties generated by anchoring filaments to glomerular basement membrane opposite podocyte foot processes and at the paramesangial angles, thereby assisting in the maintenance of capillary organization and convolution. On the capillary lumen side, mesangial cells are in direct contact with endothelial cells without an intervening basement membrane.

http://purl.obolibrary.org/obo/HP_0001966

Mesangial cells constitute the central stalk of the glomerulus and are in continuity with the extraglomerular mesangium and the juxtaglomerular apparatus. They have contractile properties generated by anchoring filaments to glomerular basement membrane opposite podocyte foot processes and at the paramesangial angles, thereby assisting in the maintenance of capillary organization and convolution. On the capillary lumen side, mesangial cells are in direct contact with endothelial cells without an intervening basement membrane.

UMLS:C4025733

An abnormality of the mesangium, i.e., of the central part of the renal glomerulus between capillaries.

Abnormality of the glomerular mesangium

Mesangial abnormality

Abnormality glomerular mesangium morphology

human_phenotype

HP:0001966

Abnormal glomerular mesangium morphology

HP:0001966

Abnormal glomerular mesangium morphology

http://purl.obolibrary.org/obo/HP_0000095

http://purl.obolibrary.org/obo/HP_0000095