loading...| Preferred Name |
Alzheimer disease |
| Synonyms |
Late-onset form of familial Alzheimer disease Alzheimer disease |
| Definitions |
A degenerative disease of the brain characterized by the insidious onset of dementia. Impairment of memory, judgment, attention span, and problem solving skills are followed by severe apraxia and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of senile plaques, neurofibrillary tangles, and neuropil threads. Note that this is a bundled term that refers to a disease rather than to phenotypic features. It is retained for convenience since Alzheimer disease is used for annotation of other diseases (e.g., Down syndrome) as if it were a feature. If possible it is preferable to annotate with the precise phenotypic features. |
| ID |
http://purl.obolibrary.org/obo/HP_0002511 |
| comment |
Note that this is a bundled term that refers to a disease rather than to phenotypic features. It is retained for convenience since Alzheimer disease is used for annotation of other diseases (e.g., Down syndrome) as if it were a feature. If possible it is preferable to annotate with the precise phenotypic features. |
| database_cross_reference |
UMLS:C1863051 SNOMEDCT_US:230267005 MONDO:0004975 MSH:C536595 DOID:10652 MSH:D000544 SNOMEDCT_US:26929004 UMLS:C0002395 |
| definition |
A degenerative disease of the brain characterized by the insidious onset of dementia. Impairment of memory, judgment, attention span, and problem solving skills are followed by severe apraxia and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of senile plaques, neurofibrillary tangles, and neuropil threads. |
| has_alternative_id |
HP:0006878 HP:0007213 |
| has_exact_synonym |
Late-onset form of familial Alzheimer disease Alzheimer disease |
| has_obo_namespace |
human_phenotype |
| id |
HP:0002511 |
| label |
Alzheimer disease |
| notation |
HP:0002511 |
| prefLabel |
Alzheimer disease |
| treeView | |
| subClassOf |