loading...| Preferred Name |
Ichthyosis |
| Synonyms |
Ichthyotic skin Hypertrophic ichthyosis Ichthyosiform abnormality of the skin |
| Definitions |
The ichthyoses are a group of skin diseases characterized by drying and scaling of skin with the accumulation of thick scales and cracks that may be painful or bleed. The abnormality in ichthyosis lies in am imbalance in the normal lifecycle of skin in which growth is matched with dying and shedding of skin cells. In ichthyosis, skin cells reproduce at a rate faster than dead skin cells can be shed or reproduce at a normal rate with a reduction in the rate of shedding. Either abnormality leads to a build up of dry and scaly skin. Note that this term refers to the morphological abnormality of the skin and not the disorder. An abnormality of the skin characterized the presence of excessive amounts of dry surface scales on the skin resulting from an abnormality of keratinization. |
| ID |
http://purl.obolibrary.org/obo/HP_0008064 |
| comment |
The ichthyoses are a group of skin diseases characterized by drying and scaling of skin with the accumulation of thick scales and cracks that may be painful or bleed. The abnormality in ichthyosis lies in am imbalance in the normal lifecycle of skin in which growth is matched with dying and shedding of skin cells. In ichthyosis, skin cells reproduce at a rate faster than dead skin cells can be shed or reproduce at a normal rate with a reduction in the rate of shedding. Either abnormality leads to a build up of dry and scaly skin. Note that this term refers to the morphological abnormality of the skin and not the disorder. |
| created_by |
peter |
| creation_date |
2008-04-02T03:41:00Z |
| database_cross_reference |
MSH:D007057 UMLS:C0020757 MEDDRA:10021198 |
| definition |
An abnormality of the skin characterized the presence of excessive amounts of dry surface scales on the skin resulting from an abnormality of keratinization. |
| has_alternative_id |
HP:0007547 HP:0000955 |
| has_exact_synonym |
Ichthyotic skin Ichthyosiform abnormality of the skin |
| has_obo_namespace |
human_phenotype |
| has_related_synonym |
Hypertrophic ichthyosis |
| id |
HP:0008064 |
| in_subset | |
| label |
Ichthyosis |
| notation |
HP:0008064 |
| prefLabel |
Ichthyosis |
| treeView | |
| subClassOf |