loading...| Preferred Name |
Tympanosclerosis |
| Synonyms |
Tympanic calcification |
| Definitions |
Plaques related to tympanosclerosis do not form spherical lesions and are typically within the drum substance itself which is normally easily discerned when using the binocular view of a microscope rather than the monocular, two-dimensional view of a hand-held otoscope. Such plaques can alter compliance of the tympanic membrane and can lead to sclerotic fixation of the ossicles, both of which can result in a mild conductive hearing loss. Histologically, lesions vary slightly according to their stage of development showing differing amounts of increased fibroblasts, abnormal fibers, areas of hyalinization, and areas of calcification into an osseous-like matrix. Most patients require no treatment. A stiffening of the tympanic membrane due to calcification, typically presents as white plaque-like lesions, involving discrete regions of the tympanic membrane and/or middle ear. |
| ID |
http://purl.obolibrary.org/obo/HP_0020123 |
| comment |
Plaques related to tympanosclerosis do not form spherical lesions and are typically within the drum substance itself which is normally easily discerned when using the binocular view of a microscope rather than the monocular, two-dimensional view of a hand-held otoscope. Such plaques can alter compliance of the tympanic membrane and can lead to sclerotic fixation of the ossicles, both of which can result in a mild conductive hearing loss. Histologically, lesions vary slightly according to their stage of development showing differing amounts of increased fibroblasts, abnormal fibers, areas of hyalinization, and areas of calcification into an osseous-like matrix. Most patients require no treatment. |
| created_by |
robinp |
| creation_date |
2019-07-02T20:36:06Z |
| definition |
A stiffening of the tympanic membrane due to calcification, typically presents as white plaque-like lesions, involving discrete regions of the tympanic membrane and/or middle ear. |
| has_exact_synonym |
Tympanic calcification |
| has_obo_namespace |
human_phenotype |
| id |
HP:0020123 |
| label |
Tympanosclerosis |
| notation |
HP:0020123 |
| prefLabel |
Tympanosclerosis |
| treeView | |
| subClassOf |