Preferred Name |
Abnormal mast cell morphology |
Synonyms |
Abnormality of mastocytes Abnormality of mast cells |
Definitions |
Mast cells (or mastocytes) can be found in several types of tissues and contain many granules rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing and defense against pathogens. Mast cells possess a non-lobed nucleus and can work with basophils in the immune defense against worms. Their cell membrane is covered with Fc recepros that may be attached to class E antibodies. Any structural anomaly of mast cells, which are found in almost all tissues and contain numerous basophilic granules and are capable of releasing large amounts of histamine and heparin upon activation. |
ID |
http://purl.obolibrary.org/obo/HP_0100494 |
comment |
Mast cells (or mastocytes) can be found in several types of tissues and contain many granules rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing and defense against pathogens. Mast cells possess a non-lobed nucleus and can work with basophils in the immune defense against worms. Their cell membrane is covered with Fc recepros that may be attached to class E antibodies. |
created_by |
doelkens |
creation_date |
2010-12-17T04:02:08Z |
database_cross_reference |
UMLS:C1301149 SNOMEDCT_US:397017008 |
definition |
Any structural anomaly of mast cells, which are found in almost all tissues and contain numerous basophilic granules and are capable of releasing large amounts of histamine and heparin upon activation. |
has_exact_synonym |
Abnormality of mastocytes Abnormality of mast cells |
has_obo_namespace |
human_phenotype |
id |
HP:0100494 |
label |
Abnormal mast cell morphology |
notation |
HP:0100494 |
prefLabel |
Abnormal mast cell morphology |
treeView | |
subClassOf |
Delete | Mapping To | Ontology | Source |
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There are currently no mappings for this class. |