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Preferred Name

人类朊蛋白病 / Human prion diseases
Definitions

Human prion diseases or transmissible spongiform encephalopathies are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a host membrane protein called 'prion protein' (PrP). Their common features are a long duration of incubation and lesions limited to the central nervous system without inflammatory or immunologic reaction but with accumulation of an abnormal form of prion protein (PrPsc).
ID

http://purl.bmicc.cn/ontology/ICD11CN/L1-8E0
definition

Human prion diseases or transmissible spongiform encephalopathies are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a host membrane protein called 'prion protein' (PrP). Their common features are a long duration of incubation and lesions limited to the central nervous system without inflammatory or immunologic reaction but with accumulation of an abnormal form of prion protein (PrPsc).
hasDbXref

http://id.who.int/icd/release/11/2019-04/mms/1965146397
label

人类朊蛋白病 / Human prion diseases
mappingRelation

http://purl.bmicc.cn/ontology/ICD10CN/A81.9
notation

L1-8E0
prefixIRI

ICD11CN:L1-8E0
prefLabel

人类朊蛋白病 / Human prion diseases
subClassOf

http://purl.bmicc.cn/ontology/ICD11CN/8
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