Preferred Name

Cirrhosis

Synonyms

Scar tissue replaces healthy tissue in the liver

Hepatic cirrhosis

Liver cirrhosis

Definitions

Cirrhosis is caused by chronic liver disease as a result of viral infections (hepatitis), alcohol abuse, certain medications, certain metabolic disorders of iron and copper, and many others. Cirrhosis may lead to a number of abnormalities including hepatomegaly, jaundice, abnormal liver function tests, ascites, dilatation of veins in the abdominal wall, anemia, and clotting deficiencies. A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function.

ID

http://purl.obolibrary.org/obo/HP_0001394

comment

Cirrhosis is caused by chronic liver disease as a result of viral infections (hepatitis), alcohol abuse, certain medications, certain metabolic disorders of iron and copper, and many others. Cirrhosis may lead to a number of abnormalities including hepatomegaly, jaundice, abnormal liver function tests, ascites, dilatation of veins in the abdominal wall, anemia, and clotting deficiencies.

Chinese label

肝硬化

database_cross_reference

MSH:D008103

SNOMEDCT_US:19943007

UMLS:C0023890

has exact synonym

Scar tissue replaces healthy tissue in the liver

Hepatic cirrhosis

has_related_synonym

Liver cirrhosis

id

HP:0001394

imported from

http://purl.obolibrary.org/obo/hp.owl

label

Cirrhosis

notation

HP:0001394

prefLabel

Cirrhosis

textual definition

A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function.

subClassOf

http://purl.obolibrary.org/obo/HP_0410042

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http://purl.obolibrary.org/obo/HP_0001394 Human Phenotype Ontology LOOM
http://purl.obolibrary.org/obo/HP_0001394 Human Phenotype Ontology SAME_URI
http://purl.bioontology.org/ontology/OMIM/MTHU002081 Online Mendelian Inheritance in Man LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2951 National Cancer Institute Thesaurus LOOM
http://purl.bioontology.org/ontology/LNC/LA9639-1 Logical Observation Identifier Names and Codes LOOM