Medical Subject Headings

Last uploaded: November 5, 2019
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Preferred Name

Cardiac Glycosides
Synonyms

Cardiotonic Steroids
Definitions

Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
ID

http://purl.bioontology.org/ontology/MESH/D002301
altLabel

Cardiotonic Steroids

Steroids, Cardiotonic

Glycosides, Cardiac
AQL

AD AE AG AI AN BI BL CF CH CL CS EC GE HI IM IP ME PD PK PO RE SD ST TO TU UR
cui

C0007158
DC

1
definition

Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
DX

19660101
Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB

0
Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D013682

http://purl.bioontology.org/ontology/MESH/D002865

http://purl.bioontology.org/ontology/MESH/D057889

http://purl.bioontology.org/ontology/MESH/D000617

http://purl.bioontology.org/ontology/MESH/D001278

http://purl.bioontology.org/ontology/MESH/D013865

http://purl.bioontology.org/ontology/MESH/D014053

http://purl.bioontology.org/ontology/MESH/D000872

http://purl.bioontology.org/ontology/MESH/D009705

http://purl.bioontology.org/ontology/MESH/D008362

http://purl.bioontology.org/ontology/MESH/D008759

http://purl.bioontology.org/ontology/MESH/D009711

http://purl.bioontology.org/ontology/MESH/D010695

http://purl.bioontology.org/ontology/MESH/D055231

http://purl.bioontology.org/ontology/MESH/D005960

http://purl.bioontology.org/ontology/MESH/D005697

http://purl.bioontology.org/ontology/MESH/D009848

http://purl.bioontology.org/ontology/MESH/D012503

http://purl.bioontology.org/ontology/MESH/D009675
isa

http://purl.bioontology.org/ontology/MESH/D004791

http://purl.bioontology.org/ontology/MESH/D002316

http://purl.bioontology.org/ontology/MESH/D000889
Mapped from

http://purl.bioontology.org/ontology/MESH/C007136

http://purl.bioontology.org/ontology/MESH/C012789

http://purl.bioontology.org/ontology/MESH/C000625591

http://purl.bioontology.org/ontology/MESH/C000621345

http://purl.bioontology.org/ontology/MESH/C042389

http://purl.bioontology.org/ontology/MESH/C016139

http://purl.bioontology.org/ontology/MESH/C062543

http://purl.bioontology.org/ontology/MESH/C091358

http://purl.bioontology.org/ontology/MESH/C010644

http://purl.bioontology.org/ontology/MESH/C000619392

http://purl.bioontology.org/ontology/MESH/C069007

http://purl.bioontology.org/ontology/MESH/C548599

http://purl.bioontology.org/ontology/MESH/C091357

http://purl.bioontology.org/ontology/MESH/C575489

http://purl.bioontology.org/ontology/MESH/C548600

http://purl.bioontology.org/ontology/MESH/C016321

http://purl.bioontology.org/ontology/MESH/C557339

http://purl.bioontology.org/ontology/MESH/C000620890

http://purl.bioontology.org/ontology/MESH/C045241

http://purl.bioontology.org/ontology/MESH/C545314

http://purl.bioontology.org/ontology/MESH/C545239

http://purl.bioontology.org/ontology/MESH/C060095

http://purl.bioontology.org/ontology/MESH/C053592

http://purl.bioontology.org/ontology/MESH/C040336

http://purl.bioontology.org/ontology/MESH/C582215

http://purl.bioontology.org/ontology/MESH/C050441

http://purl.bioontology.org/ontology/MESH/C062787

http://purl.bioontology.org/ontology/MESH/C000625592

http://purl.bioontology.org/ontology/MESH/C000602433

http://purl.bioontology.org/ontology/MESH/C582216

http://purl.bioontology.org/ontology/MESH/C000593569

http://purl.bioontology.org/ontology/MESH/C003352

http://purl.bioontology.org/ontology/MESH/C000593283

http://purl.bioontology.org/ontology/MESH/C027817

http://purl.bioontology.org/ontology/MESH/C571267

http://purl.bioontology.org/ontology/MESH/C069008

http://purl.bioontology.org/ontology/MESH/C573363

http://purl.bioontology.org/ontology/MESH/C574660

http://purl.bioontology.org/ontology/MESH/C478419

http://purl.bioontology.org/ontology/MESH/C026482
MDA

19990101
MMR

20160527
MN

D04.210.500.155.580

D09.408.180
notation

D002301
PA

D000889

D002316

D004791
prefLabel

Cardiac Glycosides
TERMUI

T006613

T006614
TH

UNK (19XX)

NLM (1966)
tui

T109

T121
subClassOf

http://purl.bioontology.org/ontology/MESH/D006027

http://purl.bioontology.org/ontology/MESH/D002297
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http://purl.bioontology.org/ontology/LNC/LP31498-6 Logical Observation Identifier Names and Codes CUI
http://purl.bioontology.org/ontology/LNC/LP31498-6 Logical Observation Identifier Names and Codes LOOM