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Last uploaded: November 5, 2019

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Preferred Name	Cathepsins
Synonyms	Cathepsin
Definitions	A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.
ID	http://purl.bioontology.org/ontology/MESH/D002403
altLabel	Cathepsin
AN	note specifics
AQL	AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0007428
DC	1
definition	A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.
DX	19650101
HN	79; was CATHEPSIN 1963-78 (Prov 1963-64)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB	EC 3.4.-
Inverse of SIB	http://purl.bioontology.org/ontology/MESH/D057055 http://purl.bioontology.org/ontology/MESH/D046988 http://purl.bioontology.org/ontology/MESH/D057057 http://purl.bioontology.org/ontology/MESH/D045726 http://purl.bioontology.org/ontology/MESH/D049069 http://purl.bioontology.org/ontology/MESH/D043484 http://purl.bioontology.org/ontology/MESH/D020689 http://purl.bioontology.org/ontology/MESH/D057056 http://purl.bioontology.org/ontology/MESH/D010450
Machine permutation	79; was CATHEPSIN 1965-78
Mapped from	http://purl.bioontology.org/ontology/MESH/C455019 http://purl.bioontology.org/ontology/MESH/C509464 http://purl.bioontology.org/ontology/MESH/C028217 http://purl.bioontology.org/ontology/MESH/C095231 http://purl.bioontology.org/ontology/MESH/C534180 http://purl.bioontology.org/ontology/MESH/C112571 http://purl.bioontology.org/ontology/MESH/C117627 http://purl.bioontology.org/ontology/MESH/C530512 http://purl.bioontology.org/ontology/MESH/C426647 http://purl.bioontology.org/ontology/MESH/C410987 http://purl.bioontology.org/ontology/MESH/C000602812 http://purl.bioontology.org/ontology/MESH/C034114 http://purl.bioontology.org/ontology/MESH/C427631 http://purl.bioontology.org/ontology/MESH/C043569 http://purl.bioontology.org/ontology/MESH/C086102 http://purl.bioontology.org/ontology/MESH/C061923 http://purl.bioontology.org/ontology/MESH/C404516 http://purl.bioontology.org/ontology/MESH/C404746 http://purl.bioontology.org/ontology/MESH/C055808 http://purl.bioontology.org/ontology/MESH/C028218 http://purl.bioontology.org/ontology/MESH/C418057 http://purl.bioontology.org/ontology/MESH/C516795 http://purl.bioontology.org/ontology/MESH/C106357 http://purl.bioontology.org/ontology/MESH/C517616 http://purl.bioontology.org/ontology/MESH/C109797 http://purl.bioontology.org/ontology/MESH/C031041 http://purl.bioontology.org/ontology/MESH/C410988 http://purl.bioontology.org/ontology/MESH/C057831 http://purl.bioontology.org/ontology/MESH/C534179
MDA	19990101
MMR	20090706
MN	D08.811.277.656.224
notation	D002403
OL	use CATHEPSINS to search CATHEPSIN 1966-78
prefLabel	Cathepsins
TERMUI	T006971 T006970
TH	NLM (1963) UNK (19XX)
tui	T116 T126
subClassOf	http://purl.bioontology.org/ontology/MESH/D010447

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/OMIM/116845	Online Mendelian Inheritance in Man	LOOM
http://purl.obolibrary.org/obo/PR_000006033	International Classification of Diseases Ontology	LOOM
http://purl.obolibrary.org/obo/PR_000006033	Protein Ontology	LOOM
http://purl.bioontology.org/ontology/LNC/LP95083-9	Logical Observation Identifier Names and Codes	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU034318	Logical Observation Identifier Names and Codes	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103232	National Cancer Institute Thesaurus	LOOM