Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
ID
http://purl.bioontology.org/ontology/MESH/D007105
altLabel
Type III Hypersensitivity
Type III Hypersensitivities
Hypersensitivities, Type III
Hypersensitivity, Type III
Diseases, Immune Complex
Immune Complex Disease
Disease, Immune Complex
AN
dis caused by deposition of antigen-antibody complexes with resultant damage to tissue; "immune complex" = IMMUNE COMPLEX see ANTIGEN-ANTIBODY COMPLEX
AQL
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
cui
C0020951
DC
1
definition
Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
DX
19740101
HN
93; was IMMUNE COMPLEX DISEASE 1972-92 (Prov 1972-73)