Pyruvate Dehydrogenase Complex

Dehydrogenase Complex, Pyruvate

A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE); dihydrolipoamide acetyltransferase; and LIPOAMIDE DEHYDROGENASE. Pyruvate dehydrogenase complex is subject to three types of control: inhibited by acetyl-CoA and NADH; influenced by the energy state of the cell; and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE catalyzes reactivation of the complex. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)

http://purl.bioontology.org/ontology/MESH/D011768

Dehydrogenase Complex, Pyruvate

Complex, Pyruvate Dehydrogenase

AD AE AI AN BI BL CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR

C0034344

1

A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE); dihydrolipoamide acetyltransferase; and LIPOAMIDE DEHYDROGENASE. Pyruvate dehydrogenase complex is subject to three types of control: inhibited by acetyl-CoA and NADH; influenced by the energy state of the cell; and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE catalyzes reactivation of the complex. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)

19740101

deficiency:Pyruvate Dehydrogenase Complex Deficiency Disease

74(73)

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000648

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

0

http://purl.bioontology.org/ontology/MESH/D015325

http://purl.bioontology.org/ontology/MESH/D013394

http://purl.bioontology.org/ontology/MESH/D000877

http://purl.bioontology.org/ontology/MESH/D063326

http://purl.bioontology.org/ontology/MESH/D050959

http://purl.bioontology.org/ontology/MESH/D046988

http://purl.bioontology.org/ontology/MESH/D048630

http://purl.bioontology.org/ontology/MESH/D056245

http://purl.bioontology.org/ontology/MESH/D056264

http://purl.bioontology.org/ontology/MESH/D045222

http://purl.bioontology.org/ontology/MESH/D011451

http://purl.bioontology.org/ontology/MESH/D003576

http://purl.bioontology.org/ontology/MESH/D045322

http://purl.bioontology.org/ontology/MESH/D010731

http://purl.bioontology.org/ontology/MESH/D014367

http://purl.bioontology.org/ontology/MESH/D054889

http://purl.bioontology.org/ontology/MESH/D000878

http://purl.bioontology.org/ontology/MESH/D042967

http://purl.bioontology.org/ontology/MESH/D013384

http://purl.bioontology.org/ontology/MESH/D007655

74

http://purl.bioontology.org/ontology/MESH/C029131

http://purl.bioontology.org/ontology/MESH/C453599

http://purl.bioontology.org/ontology/MESH/C045867

http://purl.bioontology.org/ontology/MESH/C489061

http://purl.bioontology.org/ontology/MESH/C489060

19990101

20080708

D08.811.600.741

D05.500.562.625

D011768

Pyruvate Dehydrogenase Complex

T034784

NLM (1973)

T116

T126

http://purl.bioontology.org/ontology/MESH/D009097