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Last uploaded: November 5, 2019

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Preferred Name	Dideoxynucleosides
Synonyms	2',3'-Dideoxynucleosides
Definitions	Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
ID	http://purl.bioontology.org/ontology/MESH/D015224
altLabel	2',3'-Dideoxynucleosides Dideoxyribonucleosides ddNus 2',3' Dideoxynucleosides
AN	antivirals & antimetabolites
AQL	AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0282384 C0012136 C0282385
DC	1
definition	Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
DX	19890101
HN	89
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB	0
Inverse of SIB	http://purl.bioontology.org/ontology/MESH/D013936 http://purl.bioontology.org/ontology/MESH/D003857 http://purl.bioontology.org/ontology/MESH/D003839 http://purl.bioontology.org/ontology/MESH/D003849 http://purl.bioontology.org/ontology/MESH/D015649 http://purl.bioontology.org/ontology/MESH/D003841
isa	http://purl.bioontology.org/ontology/MESH/D000998 http://purl.bioontology.org/ontology/MESH/D018894 http://purl.bioontology.org/ontology/MESH/D000963
Machine permutation	89
Mapped from	http://purl.bioontology.org/ontology/MESH/C050220 http://purl.bioontology.org/ontology/MESH/C057503 http://purl.bioontology.org/ontology/MESH/C029953 http://purl.bioontology.org/ontology/MESH/C078964 http://purl.bioontology.org/ontology/MESH/C483773 http://purl.bioontology.org/ontology/MESH/C039914 http://purl.bioontology.org/ontology/MESH/C068370 http://purl.bioontology.org/ontology/MESH/C077831 http://purl.bioontology.org/ontology/MESH/C114206 http://purl.bioontology.org/ontology/MESH/C000594692 http://purl.bioontology.org/ontology/MESH/C095793 http://purl.bioontology.org/ontology/MESH/C083225 http://purl.bioontology.org/ontology/MESH/C113088 http://purl.bioontology.org/ontology/MESH/C090028 http://purl.bioontology.org/ontology/MESH/C051073 http://purl.bioontology.org/ontology/MESH/C048808 http://purl.bioontology.org/ontology/MESH/C027799 http://purl.bioontology.org/ontology/MESH/C492871 http://purl.bioontology.org/ontology/MESH/C059513 http://purl.bioontology.org/ontology/MESH/C084453 http://purl.bioontology.org/ontology/MESH/C002854 http://purl.bioontology.org/ontology/MESH/C499741 http://purl.bioontology.org/ontology/MESH/C113812 http://purl.bioontology.org/ontology/MESH/C068372 http://purl.bioontology.org/ontology/MESH/C074658 http://purl.bioontology.org/ontology/MESH/C062823 http://purl.bioontology.org/ontology/MESH/C060054 http://purl.bioontology.org/ontology/MESH/C479242 http://purl.bioontology.org/ontology/MESH/C055315 http://purl.bioontology.org/ontology/MESH/C055437 http://purl.bioontology.org/ontology/MESH/C047920 http://purl.bioontology.org/ontology/MESH/C080961 http://purl.bioontology.org/ontology/MESH/C522559 http://purl.bioontology.org/ontology/MESH/C019336 http://purl.bioontology.org/ontology/MESH/C522560 http://purl.bioontology.org/ontology/MESH/C069735 http://purl.bioontology.org/ontology/MESH/C011160 http://purl.bioontology.org/ontology/MESH/C078819 http://purl.bioontology.org/ontology/MESH/C019252 http://purl.bioontology.org/ontology/MESH/C058925 http://purl.bioontology.org/ontology/MESH/C076821 http://purl.bioontology.org/ontology/MESH/C055457 http://purl.bioontology.org/ontology/MESH/C024082 http://purl.bioontology.org/ontology/MESH/C095792 http://purl.bioontology.org/ontology/MESH/C053666 http://purl.bioontology.org/ontology/MESH/C059694 http://purl.bioontology.org/ontology/MESH/C106538 http://purl.bioontology.org/ontology/MESH/C532172 http://purl.bioontology.org/ontology/MESH/C073006 http://purl.bioontology.org/ontology/MESH/C028788 http://purl.bioontology.org/ontology/MESH/C059696 http://purl.bioontology.org/ontology/MESH/C040052 http://purl.bioontology.org/ontology/MESH/C065053 http://purl.bioontology.org/ontology/MESH/C058238 http://purl.bioontology.org/ontology/MESH/C058924 http://purl.bioontology.org/ontology/MESH/C113790 http://purl.bioontology.org/ontology/MESH/C067409 http://purl.bioontology.org/ontology/MESH/C076776 http://purl.bioontology.org/ontology/MESH/C090029 http://purl.bioontology.org/ontology/MESH/C040623 http://purl.bioontology.org/ontology/MESH/C522653 http://purl.bioontology.org/ontology/MESH/C099324 http://purl.bioontology.org/ontology/MESH/C585686 http://purl.bioontology.org/ontology/MESH/C529139 http://purl.bioontology.org/ontology/MESH/C096098 http://purl.bioontology.org/ontology/MESH/C052693 http://purl.bioontology.org/ontology/MESH/C076282 http://purl.bioontology.org/ontology/MESH/C048809 http://purl.bioontology.org/ontology/MESH/C080962 http://purl.bioontology.org/ontology/MESH/C059695
MDA	19880512
MMR	19950608
MN	D13.570.230.500
notation	D015224
PA	D000998 D000963 D018894
prefLabel	Dideoxynucleosides
TERMUI	T044533 T044532 T044535 T044534
TH	UNK (19XX) NLM (1990) NLM (1989)
tui	T114
subClassOf	http://purl.bioontology.org/ontology/MESH/D003853

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