loading...| Preferred Name |
Didanosine |
| Synonyms |
Videx |
| Definitions |
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite. |
| ID |
http://purl.bioontology.org/ontology/MESH/D016049 |
| altLabel |
Videx Inosine, 2',3'-dideoxy- ddI (Antiviral) Dideoxyinosine NSC 612049 2',3' Dideoxyinosine NSC612049 NSC-612049 2',3'-Dideoxyinosine |
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
| cui |
C0702047 C0012133 C0592249 |
| DC |
1 |
| definition |
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite. |
| DX |
19900101 |
| HN |
92; was DIDEOXYINOSINE 1990-91 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 |
| Inverse of RB |
0 K3GDH6OH08 |
| Inverse of SIB |
http://purl.bioontology.org/ontology/MESH/D016047 http://purl.bioontology.org/ontology/MESH/D018119 http://purl.bioontology.org/ontology/MESH/D013868 http://purl.bioontology.org/ontology/MESH/D015215 |
| isa |
http://purl.bioontology.org/ontology/MESH/D018894 |
| LT |
TRD |
| Machine permutation |
92; was DIDEOXYINOSINE 1990-91 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C083218 http://purl.bioontology.org/ontology/MESH/C560264 http://purl.bioontology.org/ontology/MESH/C106062 http://purl.bioontology.org/ontology/MESH/C403504 http://purl.bioontology.org/ontology/MESH/C107380 http://purl.bioontology.org/ontology/MESH/C073075 |
| MDA |
19890714 |
| MMR |
20170524 |
| MN |
D13.570.800.573.130 D13.570.583.616.130 D03.633.100.759.590.616.130 D13.570.230.500.090 |
| notation |
D016049 |
| OL |
use DIDANOSINE to search DIDEOXYINOSINE 1990-91 |
| PA |
D019380 D000963 D018894 |
| prefLabel |
Didanosine |
| RR |
69655-05-6 (Didanosine) |
| TERMUI |
T047684 T047683 T047688 T047687 T047686 T047685 |
| TH |
FDA SRS (2014) USP (19XX) USAN (1990) US NL IE NLM (1992) DE NLM (1990) BAN (19XX) CA AU MX FR INN (19XX) UK ES |
| tui |
T121 T114 |
| subClassOf |