loading...| Preferred Name |
Lupus Coagulation Inhibitor |
| Synonyms |
Lupus Anticoagulant |
| Definitions |
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications. |
| ID |
http://purl.bioontology.org/ontology/MESH/D016682 |
| altLabel |
Lupus Anticoagulant Coagulation Inhibitor, Lupus Anticoagulant, Lupus Inhibitor, Lupus Coagulation |
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PO RE TO TU UL UR |
| cui |
C0085240 |
| DC |
1 |
| definition |
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications. |
| DX |
19920101 |
| FX |
D016736 |
| HN |
92; was LUPUS COAGULATION INHIBITOR (NM) 1978-91 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 |
| Inverse of RB |
0 |
| Inverse of RO | |
| Inverse of SIB |
http://purl.bioontology.org/ontology/MESH/D017293 http://purl.bioontology.org/ontology/MESH/D017153 |
| isa | |
| Machine permutation |
92; LUPUS COAGULATION INHIBITOR was indexed under BLOOD COAGULATION FACTORS/immunology 1986-91 & BLOOD COAGULATION FACTORS/antagonists & inhibitors 1978-88 |
| MDA |
19910712 |
| MMR |
20050719 |
| MN |
D12.776.124.486.485.114.323.210.600 D12.776.124.790.651.114.323.210.600 D12.776.377.715.548.114.323.210.600 D23.113.475 |
| notation |
D016682 |
| OL |
use LUPUS COAGULATION INHIBITOR (NM) to search LUPUS COAGULATION INHIBITOR 1980-91 |
| PA |
D007155 |
| prefLabel |
Lupus Coagulation Inhibitor |
| TERMUI |
T049969 T049970 T049972 T049968 T049971 |
| TH |
NLM (1998) NLM (1992) |
| tui |
T116 T129 |
| subClassOf |