loading...| Preferred Name |
Apoptosis |
| Synonyms |
Apoptosis, Intrinsic Pathway |
| Definitions |
Apoptosis that is triggered via cell stress and mitochondrial damage. |
| ID |
http://purl.bioontology.org/ontology/MESH/D017209 |
| altLabel |
Apoptosis, Intrinsic Pathway Programmed Cell Death, Type I Apoptoses, Extrinsic Pathway Extrinsic Pathway Apoptoses Apoptoses, Intrinsic Pathway Intrinsic Pathway Apoptoses Apoptosis, Extrinsic Pathway Extrinsic Pathway Apoptosis Intrinsic Pathway Apoptosis |
| AN |
do not confuse with NECROSIS, pathological cell death; unspecified probably goes here; PROGRAMMED CELL DEATH, TYPE II see AUTOPHAGY is also available |
| AQL |
DE GE IM PH RE |
| cui |
C1720827 C0162638 C1720828 |
| DC |
1 |
| definition |
Apoptosis that is triggered via cell stress and mitochondrial damage. One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. Apoptosis that is triggered via CELL SURFACE RECEPTORS such as TUMOR NECROSIS FACTOR RECEPTORS and DEATH DOMAIN RECEPTORS. |
| DX |
19930101 |
| FX |
D053418 D041722 D020169 D053468 D029563 D009336 D020287 |
| HN |
93 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000235 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D020169 http://purl.bioontology.org/ontology/MESH/D053418 http://purl.bioontology.org/ontology/MESH/D017637 http://purl.bioontology.org/ontology/MESH/D016923 http://purl.bioontology.org/ontology/MESH/D009336 http://purl.bioontology.org/ontology/MESH/D041722 http://purl.bioontology.org/ontology/MESH/D020170 http://purl.bioontology.org/ontology/MESH/D029563 http://purl.bioontology.org/ontology/MESH/D020287 |
| Inverse of SIB | |
| Machine permutation |
93 |
| MDA |
19920507 |
| MMR |
20160115 |
| MN |
G04.146.160 |
| notation |
D017209 |
| prefLabel |
Apoptosis |
| TERMUI |
T051308 T663494 T615426 T663495 |
| TH |
NLM (2006) NLM (1993) NLM (2007) |
| tui |
T116 T043 T123 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17557 | National Cancer Institute Thesaurus | LOOM |