loading...| Preferred Name |
Genes, erbA |
| Synonyms |
v-erbA Gene |
| Definitions |
Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity. |
| ID |
http://purl.bioontology.org/ontology/MESH/D018776 |
| altLabel |
v-erbA Gene c erbA Proto Oncogenes Genes, TR alpha beta Gene, TR Genes, erbA-alpha erbA Genes TR beta Gene erbA Gene erbA beta Gene Genes, THRA Genes, erbA alpha TR beta Genes alpha Genes, erbA c-erbA Gene erbA alpha Genes Genes, erbA-beta beta Gene, erbA Gene, THRA alpha Gene, erbA v erbA Oncogenes erbA-alpha Gene beta Genes, erbA THRB Gene erbA-beta Genes TR-beta Gene v-erbA Oncogenes alpha Gene, TR alpha Genes, TR Genes, erbA beta THRB Genes TR-alpha Genes v erbA Genes TR-beta Genes c-erbA Proto-Oncogenes Gene, THRB TR alpha Gene v-erbA Genes TR alpha Genes beta Genes, TR Genes, TR-beta erbA beta Genes v-erbA Oncogene c erbA Genes erbA alpha Gene Genes, TR-alpha erbA-beta Gene Genes, THRB THRA Gene c-erbA Genes erbA-alpha Genes c-erbA Proto-Oncogene Genes, TR beta THRA Genes TR-alpha Gene |
| AN |
erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA |
| AQL |
DE ES GE IM PH RE |
| cui |
C0242987 C0242990 C0242991 C0242988 C0242989 |
| DC |
1 |
| definition |
Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity. Viral oncogenes that are homologues of erbA1 (THRA) gene which encodes thyroid hormone receptor alpha. v-erbA Oncogenes potentiate the transforming ability of other oncogenes such as v-erbB by inhibiting spontaneous differentiation of already transformed cells. |
| DX |
19950101 |
| FX |
D011988 D018774 |
| HN |
95 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000235 |
| Inverse of RO | |
| Inverse of SIB |
http://purl.bioontology.org/ontology/MESH/D016758 http://purl.bioontology.org/ontology/MESH/D016313 http://purl.bioontology.org/ontology/MESH/D020570 http://purl.bioontology.org/ontology/MESH/D016762 http://purl.bioontology.org/ontology/MESH/D016236 http://purl.bioontology.org/ontology/MESH/D019254 http://purl.bioontology.org/ontology/MESH/D019940 http://purl.bioontology.org/ontology/MESH/D018815 http://purl.bioontology.org/ontology/MESH/D016259 http://purl.bioontology.org/ontology/MESH/D011905 http://purl.bioontology.org/ontology/MESH/D016391 http://purl.bioontology.org/ontology/MESH/D020573 |
| Machine permutation |
95 |
| MDA |
19940523 |
| MMR |
20080708 |
| MN |
G05.360.340.024.340.375.500.791.290 |
| notation |
D018776 |
| prefLabel |
Genes, erbA |
| TERMUI |
T479645 T055910 T055920 T055917 T055911 T055912 T055909 T055916 T055914 T479646 T055919 T055915 T055908 T055913 T055921 T055918 |
| TH |
NLM (2003) NLM (1995) |
| tui |
T028 |
| subClassOf |