A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
ID
http://purl.bioontology.org/ontology/MESH/D020961
altLabel
Lewy Body Type Senile Dementia
Lewy Body Disease, Cortical
Cortical Lewy Body Disease
Lewy Body Disease, Diffuse
Lewy Body Dementia
Diffuse Lewy Body Disease
Dementia, Lewy Body
AN
LEWY BODY PARKINSON DISEASE see PARKINSON DISEASE is also available
AQL
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
cui
C0752347
DC
1
definition
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
DX
20000101
FX
D016631
HN
2000; use PARKINSON DISEASE 1992-1999; for DIFFUSE LEWY BODY DISEASE & LEWY BODY DISEASE, DIFFUSE use PARKINSON DISEASE 1992-1999
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