A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
ID
http://purl.bioontology.org/ontology/MESH/D050892
altLabel
Monomethylglycine Dehydrogenase
Sarcosine N Demethylase
Sarcosine N-Demethylase
Dehydrogenase, Sarcosine
Dehydrogenase, Monomethylglycine
N-Demethylase, Sarcosine
AQL
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui
C0074059
DC
1
definition
A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
DX
20060101
HN
2006(1976); use OXIDOREDUCTASES, N-DEMETHYLATING, & SARCOSINE 1976-1979