National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Chromatin Immunoprecipitation

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C106048

code

C106048

DEFINITION

A technique that utilizes immunoprecipitation to find protein-DNA interactions in a biological sample. First, the sample is treated causing the formation of protein-chromatin crosslinks. Then, the sample is sheared to separate individual protein-DNA complexes. Finally, an antibody directed against a protein of interest is applied and the protein-DNA complexes are immunoprecipitated.

FULL_SYN

ChIP

label

Chromatin Immunoprecipitation

Preferred_Name

Chromatin Immunoprecipitation

prefixIRI

C106048

prefLabel

Chromatin Immunoprecipitation

Semantic_Type

Molecular Biology Research Technique

UMLS_CUI

C1328856

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19770

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http://purl.bioontology.org/ontology/MESH/D047369 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/OBI_00001975 Evidence and Conclusion Ontology LOOM
http://purl.obolibrary.org/obo/OBI_00001975 Ontology for Biomedical Investigations LOOM