Preferred Name |
Anaphylaxis |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C107101 |
ALT_DEFINITION |
An acute, severe multi-systemic allergic reaction that may include itching, hives, angioedema, abdominal pain, vomiting, diarrhea, breathing and swallowing difficulties, and hypotension which may progress to shock and death. A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death. |
code |
C107101 |
Concept_In_Subset | |
Contributing_Source |
NICHD MedDRA CTCAE |
DEFINITION |
An acute hypersensitive immune response that occurs from exposure to an allergen. It results from the release of histamine and histamine-like substances from mast cells, and can present with breathing difficulty due to narrowed airways, dizziness and hypotension, skin rash, weak pulse, nausea and vomiting. |
Has_NICHD_Parent | |
label |
Anaphylaxis |
NICHD_Hierarchy_Term |
Anaphylaxis |
Preferred_Name |
Anaphylaxis |
prefixIRI |
C107101 |
prefLabel |
Anaphylaxis |
Semantic_Type |
Disease or Syndrome |
UMLS_CUI |
C0002792 |
subClassOf |