National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Alloisoleucine

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118884

CAS_Registry

1509-34-8

CHEBI_ID

CHEBI:43433

code

C118884

DEFINITION

The optically active form of the amino acid alloisoleucine with an L-(2S,3R)-configuration, derived from endogenous L-isoleucine, that is an intermediate in the metabolism of branched-chain amino acids. Detection of alloisoleucine in plasma is diagnostic for maple-syrup urine disease (MSUD).

FULL_SYN

L-Isoleucine, Allo-

L-Isoleucine, 3-Methyl-, Threo-

AlloI

Allo-L-Isoleucine

Allo-Ile

Norvaline, 3-Methyl-, Threo-

L-Norvaline, 3-Methyl-, Threo-

Alloisoleucine, L-

(2S,3R)-2-Amino-3-Methylpentanoic Acid

Pentanoic Acid, 2-Amino-3-Methyl-, (S-(R*,S*))-

L-Isoleucine, Threo-

Isoleucine, Allo-

Isoleucine, Threo-

label

Alloisoleucine

Preferred_Name

Alloisoleucine

prefixIRI

C118884

prefLabel

Alloisoleucine

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0002139

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73539

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http://purl.bioontology.org/ontology/LNC/MTHU009835 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/CHEBI_22359 Chemical Entities of Biological Interest Ontology LOOM
http://purl.bioontology.org/ontology/LNC/LP14333-6 Logical Observation Identifier Names and Codes LOOM