loading...| Preferred Name |
Endothelin-1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1285 |
| ALT_DEFINITION |
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63) |
| code |
C1285 |
| DEFINITION |
Endothelin-1, encoded by the EDN1 gene is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelin-1 inhibits active Na-K transport by inhibiting Na(+)-K(+)-ATPase in intact renaltubular epithelial cells. (From OMIM, PubMed and NCI) |
| FULL_SYN |
EDN1 ET-1 Endothelin 1 |
| label |
Endothelin-1 |
| Legacy_Concept_Name |
Endothelin-1 |
| OMIM_Number |
131240 |
| Preferred_Name |
Endothelin-1 |
| prefixIRI |
C1285 |
| prefLabel |
Endothelin-1 |
| Semantic_Type |
Hormone Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P05305 |
| UMLS_CUI |
C0079281 |
| subClassOf |