National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Cyclooxygenase Inhibitor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1323

ALT_DEFINITION

A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and treatment of cancer. COX inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.

CHEBI_ID

CHEBI:35544

code

C1323

DEFINITION

Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including prostaglandins, prostacyclin and thromboxane, from arachidonic acid. Cyclooxygenase inhibitors are a type of non-steroidal anti-inflammatory drug.

FULL_SYN

COX Inhibitor

Prostaglandin G/H Synthase Inhibitor

Clyclooxygenases Inhibitor

label

Cyclooxygenase Inhibitor

Legacy_Concept_Name

Cyclooxygenase_Inhibitor

Preferred_Name

Cyclooxygenase Inhibitor

prefixIRI

C1323

prefLabel

Cyclooxygenase Inhibitor

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0085387

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C257

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
There are currently no mappings for this class.