National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Vitamin B6

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1334

ALT_DEFINITION

Class of water-soluble vitamins that are coenzymes in the metabolism of amino acids, glycogen, and sphingoid bases. (DRI)

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Vitamin B6 helps keep nerves and skin healthy, fight infections, keep blood sugar levels normal, produce red blood cells, and some enzymes work properly. Vitamin B6 is a group of related compounds (pyridoxine, pyridoxal, and pyridoxamine) found in cereals, beans, peas, nuts, meat, poultry, fish, eggs, and bananas. It is water-soluble (can dissolve in water). Not enough vitamin B6 can cause mouth and tongue sores and nervous disorders. Vitamin B6 is being studied in the prevention of hand-foot syndrome (a disorder caused by certain anticancer drugs and marked by pain, swelling, numbness, tingling, or redness of the hands or feet).

CAS_Registry

8059-24-3

CHEBI_ID

CHEBI:27306

code

C1334

Contributing_Source

CRCH

DEFINITION

A group of water-soluble vitamins essential for metabolism and normal physiological functions. B6 vitamins, including pyridoxine, pyridoxal, and pyridoxamine, are converted in vivo to pyridoxal phosphate, a cofactor necessary for the synthesis of amino acids, neurotransmitters, and sphingolipids. More than 100 enzymes involved in protein metabolism require vitamin B6 as a cofactor. Vitamin B6 is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels. Vitamin B6 is found in a wide variety of foods including cereals, beans, meat, poultry, fish, and some fruits and vegetables. (NCI04)

FULL_SYN

VIT B6

Vitamin B-6

INFOODS

VITB6A

label

Vitamin B6

Legacy_Concept_Name

Vitamin_B6

Micronutrient

Y

Nutrient

Y

Preferred_Name

Vitamin B6

prefixIRI

C1334

prefLabel

Vitamin B6

Semantic_Type

Chemical Viewed Functionally

Tolerable_Level

Y

UMLS_CUI

C0087162

Unit

mg

US_Recommended_Intake

Y

USDA_ID

415

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45812

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http://purl.bioontology.org/ontology/LNC/LP31694-0 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/MESH/D025101 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/CHEBI_27306 Chemical Entities of Biological Interest Ontology LOOM