National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Oxygen Radical

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1421

ALT_DEFINITION

Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN, SUPEROXIDES, PEROXIDES, HYDROXYL RADICAL and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS, PROTEINS, and LIPIDS.

CHEBI_ID

CHEBI:26523

CHEBI:61073

code

C1421

DEFINITION

Organic or inorganic chemicals that contain an oxygen atom with an unpaired electron. This unstable electron configuration causes these chemicals to be highly reactive with other molecules.

FULL_SYN

Oxygen Radicals

Reactive Oxygen Species

ROS

label

Oxygen Radical

Legacy_Concept_Name

Oxygen_Radicals

Preferred_Name

Oxygen Radical

prefixIRI

C1421

prefLabel

Oxygen Radical

Semantic_Type

Chemical Viewed Functionally

Element, Ion, or Isotope

UMLS_CUI

C0162772

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C512

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http://purl.obolibrary.org/obo/CHEBI_61073 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_61073 Cell Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_61073 Ontology for Biomedical Investigations LOOM