Preferred Name |
Coagulation Factor VII |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16570 |
CAS_Registry |
9001-25-6 |
code |
C16570 |
DEFINITION |
Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation. |
DesignNote |
Coagulation factor VII is converted from a zymogen to an active protease through a single proteolytic cleavage by by factor Xa, factor XIIa, factor IXa, or thrombin. (UniProt) |
FULL_SYN |
EC 3.4.21.21 Serum Prothrombin Conversion Accelerator Factor VII F7 Eptacog Alfa Proconvertin |
label |
Coagulation Factor VII |
Legacy_Concept_Name |
Coagulation_Factor-VII |
OMIM_Number |
613878 |
Preferred_Name |
Coagulation Factor VII |
prefixIRI |
C16570 |
prefLabel |
Coagulation Factor VII |
Semantic_Type |
Enzyme Amino Acid, Peptide, or Protein |
Swiss_Prot |
P08709 |
UMLS_CUI |
C0015502 |
subClassOf |