National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Coagulation Factor VII

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16570

CAS_Registry

9001-25-6

code

C16570

DEFINITION

Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation.

DesignNote

Coagulation factor VII is converted from a zymogen to an active protease through a single proteolytic cleavage by by factor Xa, factor XIIa, factor IXa, or thrombin. (UniProt)

FULL_SYN

EC 3.4.21.21

Serum Prothrombin Conversion Accelerator

Factor VII

F7

Eptacog Alfa

Proconvertin

label

Coagulation Factor VII

Legacy_Concept_Name

Coagulation_Factor-VII

OMIM_Number

613878

Preferred_Name

Coagulation Factor VII

prefixIRI

C16570

prefLabel

Coagulation Factor VII

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

Swiss_Prot

P08709

UMLS_CUI

C0015502

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17123

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16354

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/613878 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/PR_000007301 Protein Ontology LOOM
http://purl.bioontology.org/ontology/LNC/LP15966-2 Logical Observation Identifier Names and Codes LOOM