National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Homeobox Gene
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16615
code	C16615
DEFINITION	A family of genes that contain a highly conserved sequence of approximately 180 nucleotides, which encode an approximately 60 amino acid helix-turn-helix DNA binding domain made up of 2 antiparallel alpha helices and one nearly perpendicular alpha helix connected by short chains of unstructured amino acid sequences. This gene family is involved in transcriptional regulation during embryonic development.
FULL_SYN	Hox Gene Homeodomain Gene Homeobox Family Gene
Gene_Encodes_Product	Homeobox Protein
label	Homeobox Gene
Legacy_Concept_Name	Homeobox_Gene
Preferred_Name	Homeobox Gene
prefixIRI	C16615
prefLabel	Homeobox Gene
Semantic_Type	Gene or Genome
UMLS_CUI	C0017347
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20420

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	There are currently no mappings for this class.