National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Histone H3

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16685

code

C16685

DEFINITION

Histone H3 is a core subunit of the eukaryotic nucleosome complex. Histones are basic nuclear proteins responsible for the nucleosome structure of chromatin. Repeating nucleosome units contain two molecules each of Histones H2A, H2B, H3, and H4 that form an octamer complex around which approximately 146 base pairs of DNA is wrapped. Linker Histone H1 interacts with DNA between nucleosome units in mediating chromatin compaction into higher order structures. (NCI)

label

Histone H3

Legacy_Concept_Name

Histone-H3

Preferred_Name

Histone H3

prefixIRI

C16685

prefLabel

Histone H3

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0019647

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16687

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/FMA_84131 Foundational Model of Anatomy LOOM
http://purl.obolibrary.org/obo/PR_000027594 Protein Ontology LOOM