loading...| Preferred Name |
Insulin-Like Growth Factor II |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16744 |
| code |
C16744 |
| DEFINITION |
Insulin-like growth factor II (180 aa, ~20 kDa) is encoded by the human IGF2 gene. This protein plays a role in cellular growth, development, and mitogenesis. |
| DesignNote |
Similar to insulin, the full length insulin-like growth factor II precursor protein is cleaved at positions 24 or 25 and at positions 91 and 180 to release a 67 or 66 amino acid growth factor and an 89 amino acid E peptide. The E peptide can be further processed to release prepeptin. (UniProt) |
| FULL_SYN |
IGF2 Somatomedin A Insulin-Like Growth Factor 2 IGF-2 Somatomedin-A IGF-II |
| label |
Insulin-Like Growth Factor II |
| Legacy_Concept_Name |
Insulin-Like_Growth_Factor-2 |
| OMIM_Number |
147470 |
| Preferred_Name |
Insulin-Like Growth Factor II |
| prefixIRI |
C16744 |
| prefLabel |
Insulin-Like Growth Factor II |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P01344 |
| UMLS_CUI |
C0021666 |
| subClassOf |