National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Integrin Alpha-X

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16789

code

C16789

DEFINITION

Integrin alpha-X (1163 aa, ~128 kDa) is encoded by the human ITGAX gene. This protein is involved in cell-matrix interactions and integrin signaling.

DesignNote

Integrin alpha-X forms a non-covalent complex with integrin beta-2 (ITGB2 or CD18) to form a leukocyte-specific integrin called inactivated-C3b (iC3b) receptor 4 (CR4).

FULL_SYN

Leukocyte Adhesion Receptor P150,95

Integrin Alpha X

CD11 Antigen-Like Family Member C

Leu M5

Axb2

CD11c

p150 95 Integrin Alpha Chain

Cr4

Alphax Integrin Chain

Leukocyte Surface Antigen P150, 95

Antigen Cd11c (P150), Alpha Polypeptide

Leukocyte Adhesion Glycoprotein P150,95, Alpha Chain

Myeloid Membrane Antigen, Alpha Subunit

ITGAX

label

Integrin Alpha-X

Legacy_Concept_Name

Integrin_Alpha-X

OMIM_Number

151510

Preferred_Name

Integrin Alpha-X

prefixIRI

C16789

prefLabel

Integrin Alpha-X

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P20702

UMLS_CUI

C0023395

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16393

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/PR_000001013 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001013 Cell Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001013 Protein Ontology LOOM
http://purl.bioontology.org/ontology/OMIM/151510 Online Mendelian Inheritance in Man LOOM