National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Mitosis

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16864

ALT_DEFINITION

The process by which a single parent cell divides to make two new daughter cells. Each daughter cell receives a complete set of chromosomes from the parent cell. This process allows the body to grow and replace cells.

code

C16864

DEFINITION

The usual process of somatic reproduction of cells consisting of a sequence of modifications of the nucleus that result in the formation of two daughter cells with exactly the same chromosome and DNA content as that of the original cell. It is the process by which the body grows and replaces cells and is divided into four phases. In Prophase, paired chromosomes form, nuclear membrane disappears, the achromatic spindle appears, and polar bodies form. In Metaphase, chromosomes are arranged in the equatorial plane of the central spindle to form the monaster and chromosomes separate into exactly similar halves. In Anaphase, the two groups of daughter chromosomes separate and move along the fibers of the central spindle, each toward one of the asters, forming the diaster. In Telophase, the daughter chromosomes resolve themselves into a reticulum, the daughter nuclei are formed, and the cytoplasm divides forming two complete daughter cells.

FULL_SYN

mitotic cycle

Mitotic Process

label

Mitosis

Legacy_Concept_Name

Mitosis

Preferred_Name

Mitosis

prefixIRI

C16864

prefLabel

Mitosis

Semantic_Type

Phenomenon or Process

UMLS_CUI

C0026255

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20349

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http://purl.bioontology.org/ontology/MESH/D008938 Medical Subject Headings LOOM