Preferred Name |
Protein Tyrosine Kinase |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17020 |
code |
C17020 |
DEFINITION |
Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain; and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (Dictionary of Cell and Molecular Biology Online) |
DesignNote |
Formerly 2.7.1.112 |
FULL_SYN |
EC 2.7.10 Tyrosine-Specific Protein Kinase Tyrosine Protein Kinase Protein-Tyrosine Kinase PTK Tyrosine Kinase |
label |
Protein Tyrosine Kinase |
Legacy_Concept_Name |
Protein_Tyrosine_Kinase |
Preferred_Name |
Protein Tyrosine Kinase |
prefixIRI |
C17020 |
prefLabel |
Protein Tyrosine Kinase |
Semantic_Type |
Enzyme Amino Acid, Peptide, or Protein |
UMLS_CUI |
C0033681 |
subClassOf |
Delete | Mapping To | Ontology | Source |
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There are currently no mappings for this class. |