National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Serine Protease

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17123

code

C17123

DEFINITION

Proteases that have a serine residue in the active center of the enzyme. These enzymes catalyze the hydrolysis of covalent peptidic bonds by serine nucleophilic attack. Serine proteases participate in a wide range of functions in the body, including blood clotting, inflammation, and digestion.

label

Serine Protease

Legacy_Concept_Name

Serine_Protease

Preferred_Name

Serine Protease

prefixIRI

C17123

prefLabel

Serine Protease

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

UMLS_CUI

C2717971

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16965

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