National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Vitronectin

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17283

ALT_DEFINITION

A blood plasma glycoprotein that mediates cell adhesion and interacts with proteins of the complement, coagulation, and fibrinolytic cascade. (From Segen, Dictionary of Modern Medicine, 1992)

fibronectin-like extracellular glycoprotein involved in cell adhesion.

code

C17283

DEFINITION

This protein is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. (LocusLink)

FULL_SYN

Somatomedin B

Serum Spreading Factor

Epibolin

VTN

Complement S-Protein

label

Vitronectin

Legacy_Concept_Name

Vitronectin

OMIM_Number

193190

Preferred_Name

Vitronectin

prefixIRI

C17283

prefLabel

Vitronectin

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P04004

UMLS_CUI

C0055023

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16393

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http://purl.bioontology.org/ontology/LNC/MTHU014695 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/LP15952-2 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/MESH/D019096 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/OMIM/193190 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/PR_000017360 Protein Ontology LOOM