National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Vasopressin Receptor

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17345

code

C17345

DEFINITION

The biologic effects of arginine vasopressin (AVP) are mediated by 3 receptor subtypes: the V1A and V1B receptors that activate phospholipases via Gq/11, and the V2 receptor that activates adenylyl cyclase by interacting with GS. This subfamily of G-protein coupled receptors also includes OXT receptors. Their activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. All are involved in the control of body fluid osmolality, blood volume, blood pressure, and vascular tone. (from OMIM)

FULL_SYN

Arginine Vasopressin Receptor

AVPR

label

Vasopressin Receptor

Legacy_Concept_Name

Vasopressin_Receptor

Preferred_Name

Vasopressin Receptor

prefixIRI

C17345

prefLabel

Vasopressin Receptor

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

UMLS_CUI

C0052360

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18239

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