National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Flavonoid

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1745

ALT_DEFINITION

A class of polyphenols which are biogenetically derived from a phenylpropane (C6-C3 unit) and three C2 units to form a benzopyran with an additional phenyl group at C-2 (C6-C3-C6 unit). They consist of 15 carbons and vary by oxidation/hydroxylation, glycosidation, and other functional groups. Historically, the benzene ring is denoted 'A'-ring, the pyran ring 'C' ring, and the phenyl ring 'B'-ring. The numbering of the phenyl ring starts with 1' (""one prime"") at the carbon that is connected to the pyran ring, and follows along the phenyl ring with C-2', -3', -4', -5', and -6'.

A member of a group of substances found in many plants and plant-based foods. Flavonoids have shown antioxidant effects.

CHEBI_ID

CHEBI:63326

CHEBI:38672

CHEBI:47916

code

C1745

Contributing_Source

CRCH

DEFINITION

One of a number of chemical compounds found in certain fruits, vegetables and seeds with antioxidant properties and potential antineoplastic properties. As polyphenolic, soluble plant pigments, flavonoids are usually subdivided into 5 subgroups flavonols, flavones, flavonones, flavan-3-ols, anthocyanidins. Although not considered essential nutrients, some flavonoids may be beneficial to health by strengthening and protecting blood vessels and connective tissue and acting as anti-inflammatory, antihistaminic, and antiviral agents. As antioxidants, some flavonoids may protect lipids from oxidative damage or retard the formation of cataracts. (NCI04)

FULL_SYN

3-Hydroxyflavone

Flavonol

Flavonols

2-Phenyl-Chromene

2-Phenyl-Benzopyran

3-Hydroxy-2-phenyl-4H-1-benzopyran-4-one

label

Flavonoid

Legacy_Concept_Name

Flavonoid

NSC_Code

57653

Preferred_Name

Flavonoid

prefixIRI

C1745

prefLabel

Flavonoid

Semantic_Type

Organic Chemical

UMLS_CUI

C0596577

Unit

mg

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28203

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http://purl.obolibrary.org/obo/CHEBI_47916 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_47916 International Classification of Diseases Ontology LOOM