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loading...| Preferred Name |
Aptamer |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1749 |
| code |
C1749 |
| DEFINITION |
Double-stranded DNA or single-stranded RNA oligonucleotide sequences with the capacity to recognize target molecules with high affinity and specificity. Fundamentally distinct from antibodies, aptamers mimic their properties and have emerged as a promising class of molecules in both therapeutic and diagnostic formats. In having small size (8-15 kDa) relative to antibodies (150 kDa), aptamers are candidates for rapid tumor penetration and blood clearance. |
| label |
Aptamer |
| Legacy_Concept_Name |
Aptamer |
| Preferred_Name |
Aptamer |
| prefixIRI |
C1749 |
| prefLabel |
Aptamer |
| Semantic_Type |
Nucleic Acid, Nucleoside, or Nucleotide |
| UMLS_CUI |
C0599013 |
| subClassOf |
Create New Mapping
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/SO_0000031 | Sequence Types and Features Ontology | LOOM | |
| http://purl.obolibrary.org/obo/CHEBI_140488 | Chemical Entities of Biological Interest Ontology | LOOM |