National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Fibroblast Growth Factor Receptor 1

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17590

code

C17590

DEFINITION

Fibroblast growth factor receptor 1 (822 aa, ~92 kDa) is encoded by the human FGFR1 gene. This protein is involved in the regulation of embryonic development, cell proliferation, cell differentiation and cellular migration.

DesignNote

At least 21 isoforms of the fibroblast growth factor receptor 1 protein have been described. They are the products of alternative splicing and exibihit tissue-specific patterns of expression.

FULL_SYN

N-sam

FGFR1

Proto-Oncogene c-Fgr

FMS-Like Tyrosine Kinase 2

Basic Fibroblast Growth Factor Receptor 1

bFGF-R-1

BFGFR

CD331 Antigen

FLT-2

EC 2.7.10.1

FGFR-1

label

Fibroblast Growth Factor Receptor 1

Legacy_Concept_Name

Fibroblast_Growth_Factor_Receptor-1

OMIM_Number

136350

Preferred_Name

Fibroblast Growth Factor Receptor 1

prefixIRI

C17590

prefLabel

Fibroblast Growth Factor Receptor 1

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

Swiss_Prot

P11362

UMLS_CUI

C0170936

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17297

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http://purl.obolibrary.org/obo/PR_000001448 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001448 Protein Ontology LOOM
http://purl.bioontology.org/ontology/OMIM/136350 Online Mendelian Inheritance in Man LOOM